Zepbound: $1,08.37 Mounjaro: $1,112.16 Orfoglipron (not yet available): $149 to $399, depending on the dose What are the side effects of GLP-1 medications
Marzioni M, Alpini G, Saccomanno S, Candelaresi C, Venter J, Rychlicki C, et al
Researchers who have never used a GLP-1 agonist should generally start with tirzepatide or even semaglutide to understand their individual response to incretin therapy before attempting a triple agonist with higher side effect rates
There are also new formulations that act on other receptors in addition to GLP-1 receptors to significantly increase the medication's effectiveness , in some cases doubling the weight reduction patients experience
Ask about currently approved alternatives
Retatrutide is an investigational compound and is legal for research purposes in the US